Make sense of insulin

Spike times make sense.

Many behavioral responses are completed too quickly for the underlying sensory processes to rely on estimation of neural firing rates over extended time windows. Theoretically, first-spike times could underlie such rapid responses, but direct evidence has been lacking. Such evidence has now been uncovered in the human somatosensory system. We discuss these findings and their potential generaliz...

Events Can Make Sense

Tame is a new event-based system for managing concurrency in network applications. Code written with Tame abstractions does not suffer from the “stackripping” problem associated with other event libraries. Like threaded code, tamed code uses standard control flow, automatically-managed local variables, and modular interfaces between callers and callees. Tame’s implementation consists of C++ lib...

Sense tagging: does it make sense?

Sense tagging is probably one of the challenges that corpus linguists have to face in the near future. So far, computerisation of this task has yielded very modest results despite numerous efforts, and sense tagging is turning out to be a touchy task. Difficulties stem from various sources, extracting disambiguating information from the context. However, one of the main problems that lies upstr...

Direct Autocrine Action of Insulin on β-Cells: Does It Make Physiological Sense?

In recent years there has been a growing interest in the possibility of a direct autocrine effect of insulin on the pancreatic β-cell. Indeed, there have been numerous intriguing articles and several eloquent reviews written on the subject (1-3); however, the concept is still controversial. Although many in vitro experiments, a few transgenic mouse studies, and some human investigations would b...

Direct Autocrine Action of Insulin on b-Cells: Does It Make Physiological Sense?